As you might have already noticed, in Windows 10 version 1511, Microsoft implemented a context menu item for Windows Defender. Now it is possible to scan selected files and folders in File Explorer with one click by right clicking and launching Windows Defender. If you do not want this "Scan with Windows Defender" verb/context menu item, here is how you can safely remove it.
There are several reasons why you might want to get rid of the mentioned context menu item. For example, you might be using some alternative antivirus software which disables Defender and provides its own context menu item to scan files and folders. Or you might have disabled Windows Defender completely and have no need for the context menu item.
To delete Scan with Windows Defender entry from the context menu in Windows 10, you can use ready-to-use Registry files I made for your convenience. The undo file is also included.
To remove the Scan with Windows Defender context menu item in Windows 10, double click the file named "remove Scan with Windows Defender.reg".
To restore the context menu item, double click the file named "restore Scan with Windows Defender.reg". It will restore the defaults.
Here is how it works.
The context menu item is represented by the following Registry entry.
To save your time, use Winaero Tweaker. It has the appropriate option under Context Menu\Remove Default Items: You can get the app here: Download Winaero Tweaker.